Commenting on the latest episode of the show, the Queens Park Rangers star tweeted that there was "strong evidence to support the breeding licence theory".
The 31-year-old used his Twitter account to provide a running commentary on the show.
He wrote: "1st viewing of this Benefits Street. What am I seeing! Is this a wind up?
"A licence to give financial advice. So on and so forth. Yet, anyone can have child? Nothing else needed except the sexual appetite."
Barton declared that the "world is f***** sometimes" and slammed one of the street's residents as a "full blown tramp".
Barton was equally harsh towards the Romanians who had come to Britain in the hope of a better life and improved working conditions.
The former Manchester City and Newcastle star wrote: "No way is this real. This is a setup. #benefitstreet #setupstreet
"To annoy people like me. Romanians. If you don't like it here. You know to do. Imagine me going to Romania trying this shit on?
"Interesting they all have cars, gold chains, mobile phones, a roof over their heads and are fat. Can't be that bad now can it."
Barton's final tweet before crashing out for the night simply read: "Off to bed. Never again. Ground control to Major Tom. This place is f****. Can I come home new please. Pretty please. xx"
He wrote: "Still not accepting that is reality. Convinced it is a setup to make people detest the benefits system. Either way it works."
Barton is one of the most prolific tweeters in Britain, with his brutally honest tweets often landing him in trouble.
Last year Barton was handed a two-game suspended ban by the French Football Federation after describing Paris St Germain's Brazilian defender Thiago Silva as an "overweight ladyboy".
The Championship star, who is hoping to lead QPR back into the Premier League this season, once branded TV presenter and former England footballer Gary Lineker an "odious little toad".
However while he often lands himself in hot water, Barton regularly tweets quotes from famous philosopher Friedrich Nietzsche and Animal Farm author George Orwell.
The 31-year-old is currently studying for a philosophy degree at Roehampton University in south London.